计算分子生物学引论

With the availability of high-throughput genomic and proteomic data, the application of mathematics and computer science have changed the face of modern biology. A substantial coreof bioinformatics or computational molecular biology methods has been developed during thepast two decades to meet the need of biological scientists for data storage, data retrieval, and mostimportantly, data analysis and scientific discovery. This course introduces the kernel ideas ofbioinformatics, reviews some of the major scientistific questions that bioinformatics can hopefully help to study, and describe selected methods in both sequence analysis and functional genomics. It is widely recognized that the research in this field is interdisciplinary in nature andrequires knowledge in computational algorithms, statistics, pattern recognition, and molecularbiology. The course is designed both for informatics students and for biology students.

Students in this class are expected to spend a substantial amount of time and effort reading research articles/monographs ranging from information science to biology. Most (if not all) the materials used in this course are in English so students are required to have reasonbly good reading ability in English. The lectures will be given in mixed English and Chinese.